Correlations are made between the pathologic findings in nude mice and some congenital cellular immunologic disorders in man. On the other hand, they are not especially susceptible to spontaneous tumor development. The presence of circulating auto-antibodies and immune-complex type glomerulonephritis in nude mice reinforces the hypothesis that spontaneous autoimmunity and B-cell hyperactivity are associated with T-cell deficiency. But their response to T-independent antigens is normal. Browse 24 siberian mouse videos and clips available to use in your projects, or start a new search to explore more footage and b-roll video clips. They also have impaired T-cell functions as demonstrated by an absence of delayed hypersensitivity reactions, an inability to reject skin allografts and a decreased antibody response to some T-dependent antigens. Nude mice lack 'thymosin', a thymic factor secreted by the epithelial cells of the thymus. However, they have T-cell precursors in their bone marrow. These mice possess a vestigial thymus which is incapable of producing mature T-cells as shown by a decreased lymphocyte population carrying the theta antigen and depleted 'thymus-dependent' areas in their peripheral lymphoid organs. Penlee House Gallery & Museum Morrab Road, Penzance, Cornwall TR18 4HE England. Tag artworks and verify existing tags by joining the Tagger community. Congenitally athymic nude mice (nu/nu) are presented as a model for the study of cell-mediated immunologic deficiencies. Nude (1,224) Puberty (1) Royal Academician (25,774) Sister (32) Towel (83) Undressed (1) Woman (8,816) Youth (149) Help improve Art UK.

Nude naked siberian mouse